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Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination

Diacylglycerol kinase γ (DGKγ) is a lipid kinase to convert diacylglycerol (DG) to phosphatidic acid (PA) and indirectly regulates protein kinase C γ (PKCγ) activity. We previously reported that the basal PKCγ upregulation impairs cerebellar long-term depression (LTD) in the conventional DGKγ knocko...

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Detalles Bibliográficos
Autores principales:	Tsumagari, Ryosuke, Maruo, Kenta, Kakizawa, Sho, Ueda, Shuji, Yamanoue, Minoru, Saito, Hiromitsu, Suzuki, Noboru, Shirai, Yasuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660329/ https://www.ncbi.nlm.nih.gov/pubmed/33114041 http://dx.doi.org/10.3390/ijms21217866

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