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A Distance-Based Framework for the Characterization of Metabolic Heterogeneity in Large Sets of Genome-Scale Metabolic Models

Gene expression and protein abundance data of cells or tissues belonging to healthy and diseased individuals can be integrated and mapped onto genome-scale metabolic networks to produce patient-derived models. As the number of available and newly developed genome-scale metabolic models increases, ne...

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Detalles Bibliográficos
Autores principales: Cabbia, Andrea, Hilbers, Peter A.J., van Riel, Natal A.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660451/
https://www.ncbi.nlm.nih.gov/pubmed/33205127
http://dx.doi.org/10.1016/j.patter.2020.100080