Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression

The COVID-19 has emerged as an epidemic, causing severe pneumonia with a high infection rate globally. To better understand the pathogenesis caused by SARS-CoV-2, we developed a rhesus macaque model to mimic natural infection via the nasal route, resulting in the SARS-CoV-2 virus shedding in the nos...

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Detalles Bibliográficos
Autores principales: Zheng, Huiwen, Li, Heng, Guo, Lei, Liang, Yan, Li, Jing, Wang, Xi, Hu, Yunguang, Wang, Lichun, Liao, Yun, Yang, Fengmei, Li, Yanyan, Fan, Shengtao, Li, Dandan, Cui, Pingfang, Wang, Qingling, Shi, Haijing, Chen, Yanli, Yang, Zening, Yang, Jinling, Shen, Dong, Cun, Wei, Zhou, Xiaofang, Dong, Xingqi, Wang, Yunchuan, Chen, Yong, Dai, Qing, Jin, Weihua, He, Zhanlong, Li, Qihan, Liu, Longding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660522/
https://www.ncbi.nlm.nih.gov/pubmed/33180882
http://dx.doi.org/10.1371/journal.ppat.1008949

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