Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

Hepatocyte nuclear factor 4α (HNF4α) is a ligand-sensing transcription factor and presents as a potential drug target in metabolic diseases and cancer. In humans, mutations in the HNF4α gene cause maturity-onset diabetes of the young (MODY), and the elevated activity of this protein has been associa...

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Detalles Bibliográficos
Autores principales: Meijer, Isabelle, Willems, Sabine, Ni, Xiaomin, Heering, Jan, Chaikuad, Apirat, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660650/
https://www.ncbi.nlm.nih.gov/pubmed/33114319
http://dx.doi.org/10.3390/ijms21217895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660650/
https://www.ncbi.nlm.nih.gov/pubmed/33114319
http://dx.doi.org/10.3390/ijms21217895

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