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Evolocumab, a PCSK9‐Monoclonal Antibody, Rapidly Reverses Coronary Artery Endothelial Dysfunction in People Living With HIV and People With Dyslipidemia
BACKGROUND: PCSK9 (proprotein convertase subtilisin/kexin type 9) is well recognized for its important role in cholesterol metabolism. Elevated levels are associated with increased cardiovascular risk and inhibition with PCSK9 antibodies (PCSK9i) lowers cardiovascular events in patients with coronar...
Autores principales: | Leucker, Thorsten M., Gerstenblith, Gary, Schär, Michael, Brown, Todd T., Jones, Steven R., Afework, Yohannes, Weiss, Robert G., Hays, Allison G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660736/ https://www.ncbi.nlm.nih.gov/pubmed/32674634 http://dx.doi.org/10.1161/JAHA.120.016263 |
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