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Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort

BACKGROUND: There have been few studies on the relationship between long‐term changes in sodium intake and blood pressure. A method of reducing sodium intake in a population that is known for high‐sodium intake based on homemade cooking is also needed. METHODS AND RESULTS: Our study was based on a b...

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Autores principales: Hou, Lei, Guo, Xiaolei, Zhang, Jiyu, Chen, Xi, Yan, Liuxia, Cai, Xiaoning, Tang, Junli, Xu, Chunxiao, Wang, Baohua, Wu, Jing, Ma, Jixiang, Xu, Aiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660739/
https://www.ncbi.nlm.nih.gov/pubmed/32674645
http://dx.doi.org/10.1161/JAHA.119.014897
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author Hou, Lei
Guo, Xiaolei
Zhang, Jiyu
Chen, Xi
Yan, Liuxia
Cai, Xiaoning
Tang, Junli
Xu, Chunxiao
Wang, Baohua
Wu, Jing
Ma, Jixiang
Xu, Aiqiang
author_facet Hou, Lei
Guo, Xiaolei
Zhang, Jiyu
Chen, Xi
Yan, Liuxia
Cai, Xiaoning
Tang, Junli
Xu, Chunxiao
Wang, Baohua
Wu, Jing
Ma, Jixiang
Xu, Aiqiang
author_sort Hou, Lei
collection PubMed
description BACKGROUND: There have been few studies on the relationship between long‐term changes in sodium intake and blood pressure. A method of reducing sodium intake in a population that is known for high‐sodium intake based on homemade cooking is also needed. METHODS AND RESULTS: Our study was based on a baseline survey of 15 350 individuals aged 18 to 69 years with multistage random sampling and a 3‐year salt‐restriction campaign across Shandong Province, China. We included 339 individuals from six districts/counties in this cohort study, and the 24‐hour urinary sodium‐potassium ratio (Na(+)/K(+)) served as an indicator of sodium intake. The average change in ratio was 2.39 (95% CI, 2.17–2.61) from 6.81 (95% CI, 6.41–7.21) at baseline to 4.41 (95% CI, 4.18–4.64) during the resurvey. Following a reduction from low to high quartiles of urinary Na(+)/K(+) ratio, the average increases were 10.9 (95% CI, 8.9–12.9), 9.2 (95% CI, 6.9–11.5), 6.3 (95% CI, 4.0–8.6), and 5.3 (95% CI, 2.9–7.7) mm Hg for systolic blood pressure (P for trend=0.019) and 3.8 (95% CI, 2.4–5.2), 2.9 (95% CI, 1.7–4.2), 1.6 (95% CI, 0.4–2.8), and −0.3 (95% CI, −1.4–0.8) mm Hg for diastolic blood pressure (P for trend=0.002), respectively. A reduction in salt intake was evident for people using a 2‐g salt‐restriction spoon for cooking (−3.49 versus −2.22; P=0.027) after adjustment of confounding factors, compared with nonusers. Similar findings were obtained for other salt‐restriction spoon–based indicators. CONCLUSIONS: Our study indicated that using a salt‐restriction spoon for cooking was associated with reduced salt intake that led to a blunting of blood pressure deterioration. This finding further supports the salt‐restriction spoon–based strategy for people whose primary salt intake is from homemade cooking.
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spelling pubmed-76607392020-11-17 Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort Hou, Lei Guo, Xiaolei Zhang, Jiyu Chen, Xi Yan, Liuxia Cai, Xiaoning Tang, Junli Xu, Chunxiao Wang, Baohua Wu, Jing Ma, Jixiang Xu, Aiqiang J Am Heart Assoc Original Research BACKGROUND: There have been few studies on the relationship between long‐term changes in sodium intake and blood pressure. A method of reducing sodium intake in a population that is known for high‐sodium intake based on homemade cooking is also needed. METHODS AND RESULTS: Our study was based on a baseline survey of 15 350 individuals aged 18 to 69 years with multistage random sampling and a 3‐year salt‐restriction campaign across Shandong Province, China. We included 339 individuals from six districts/counties in this cohort study, and the 24‐hour urinary sodium‐potassium ratio (Na(+)/K(+)) served as an indicator of sodium intake. The average change in ratio was 2.39 (95% CI, 2.17–2.61) from 6.81 (95% CI, 6.41–7.21) at baseline to 4.41 (95% CI, 4.18–4.64) during the resurvey. Following a reduction from low to high quartiles of urinary Na(+)/K(+) ratio, the average increases were 10.9 (95% CI, 8.9–12.9), 9.2 (95% CI, 6.9–11.5), 6.3 (95% CI, 4.0–8.6), and 5.3 (95% CI, 2.9–7.7) mm Hg for systolic blood pressure (P for trend=0.019) and 3.8 (95% CI, 2.4–5.2), 2.9 (95% CI, 1.7–4.2), 1.6 (95% CI, 0.4–2.8), and −0.3 (95% CI, −1.4–0.8) mm Hg for diastolic blood pressure (P for trend=0.002), respectively. A reduction in salt intake was evident for people using a 2‐g salt‐restriction spoon for cooking (−3.49 versus −2.22; P=0.027) after adjustment of confounding factors, compared with nonusers. Similar findings were obtained for other salt‐restriction spoon–based indicators. CONCLUSIONS: Our study indicated that using a salt‐restriction spoon for cooking was associated with reduced salt intake that led to a blunting of blood pressure deterioration. This finding further supports the salt‐restriction spoon–based strategy for people whose primary salt intake is from homemade cooking. John Wiley and Sons Inc. 2020-07-17 /pmc/articles/PMC7660739/ /pubmed/32674645 http://dx.doi.org/10.1161/JAHA.119.014897 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Hou, Lei
Guo, Xiaolei
Zhang, Jiyu
Chen, Xi
Yan, Liuxia
Cai, Xiaoning
Tang, Junli
Xu, Chunxiao
Wang, Baohua
Wu, Jing
Ma, Jixiang
Xu, Aiqiang
Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title_full Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title_fullStr Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title_full_unstemmed Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title_short Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na(+)/K(+) Ratios and Blood Pressure: Findings From a Population‐Based Cohort
title_sort associations between salt‐restriction spoons and long‐term changes in urinary na(+)/k(+) ratios and blood pressure: findings from a population‐based cohort
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660739/
https://www.ncbi.nlm.nih.gov/pubmed/32674645
http://dx.doi.org/10.1161/JAHA.119.014897
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