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Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015

BACKGROUND: No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. METHODS AND RESULTS: We utilized the Surveillance, Epidemiology, and End Results (SEE...

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Autores principales: Antwi‐Amoabeng, Daniel, Meghji, Zahara, Thakkar, Samarthkumar, Ulanja, Mark B., Taha, Mohamed, Adalja, Devina, Al‐Khafaji, Jaafar, Gullapalli, Nageshwara, Beutler, Bryce D., Boampong‐Konam, Killian, Doshi, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660836/
https://www.ncbi.nlm.nih.gov/pubmed/32389047
http://dx.doi.org/10.1161/JAHA.119.014846
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author Antwi‐Amoabeng, Daniel
Meghji, Zahara
Thakkar, Samarthkumar
Ulanja, Mark B.
Taha, Mohamed
Adalja, Devina
Al‐Khafaji, Jaafar
Gullapalli, Nageshwara
Beutler, Bryce D.
Boampong‐Konam, Killian
Doshi, Rajkumar
author_facet Antwi‐Amoabeng, Daniel
Meghji, Zahara
Thakkar, Samarthkumar
Ulanja, Mark B.
Taha, Mohamed
Adalja, Devina
Al‐Khafaji, Jaafar
Gullapalli, Nageshwara
Beutler, Bryce D.
Boampong‐Konam, Killian
Doshi, Rajkumar
author_sort Antwi‐Amoabeng, Daniel
collection PubMed
description BACKGROUND: No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. METHODS AND RESULTS: We utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database from the National Cancer Institute for all PMCTs diagnosed between 1973 and 2015. From a total of 7 384 580 cases of cancer registered in SEER, we identified 327 men and 367 women with PMCTs. The majority (78%) of patients were white. Sarcoma was the most common type of PMCT in both men and women (≈60%). Individuals diagnosed with lymphoma exhibited better survival than those with other types of PMCTs. Men were diagnosed at a younger age than women; however, there was no significant difference in overall survival between the sexes. Men diagnosed with PMCT between the ages of 51 and 65 years demonstrated prolonged survival compared with those diagnosed at younger or older ages. There was no difference in survival rates among women based on age at diagnosis. CONCLUSIONS: PMCTs are rare in both men and women. Tumors tend to be diagnosed at an earlier age in men compared with women, but there is no sex disparity in survival rate. Sarcoma is the most common type of PMCT, and lymphoma is associated with the highest survival rate among both sexes.
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spelling pubmed-76608362020-11-17 Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 Antwi‐Amoabeng, Daniel Meghji, Zahara Thakkar, Samarthkumar Ulanja, Mark B. Taha, Mohamed Adalja, Devina Al‐Khafaji, Jaafar Gullapalli, Nageshwara Beutler, Bryce D. Boampong‐Konam, Killian Doshi, Rajkumar J Am Heart Assoc Original Research BACKGROUND: No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. METHODS AND RESULTS: We utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database from the National Cancer Institute for all PMCTs diagnosed between 1973 and 2015. From a total of 7 384 580 cases of cancer registered in SEER, we identified 327 men and 367 women with PMCTs. The majority (78%) of patients were white. Sarcoma was the most common type of PMCT in both men and women (≈60%). Individuals diagnosed with lymphoma exhibited better survival than those with other types of PMCTs. Men were diagnosed at a younger age than women; however, there was no significant difference in overall survival between the sexes. Men diagnosed with PMCT between the ages of 51 and 65 years demonstrated prolonged survival compared with those diagnosed at younger or older ages. There was no difference in survival rates among women based on age at diagnosis. CONCLUSIONS: PMCTs are rare in both men and women. Tumors tend to be diagnosed at an earlier age in men compared with women, but there is no sex disparity in survival rate. Sarcoma is the most common type of PMCT, and lymphoma is associated with the highest survival rate among both sexes. John Wiley and Sons Inc. 2020-05-10 /pmc/articles/PMC7660836/ /pubmed/32389047 http://dx.doi.org/10.1161/JAHA.119.014846 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Antwi‐Amoabeng, Daniel
Meghji, Zahara
Thakkar, Samarthkumar
Ulanja, Mark B.
Taha, Mohamed
Adalja, Devina
Al‐Khafaji, Jaafar
Gullapalli, Nageshwara
Beutler, Bryce D.
Boampong‐Konam, Killian
Doshi, Rajkumar
Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title_full Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title_fullStr Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title_full_unstemmed Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title_short Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
title_sort survival differences in men and women with primary malignant cardiac tumor: an analysis using the surveillance, epidemiology and end results (seer) database from 1973 to 2015
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660836/
https://www.ncbi.nlm.nih.gov/pubmed/32389047
http://dx.doi.org/10.1161/JAHA.119.014846
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