Leveraging functional annotation to identify genes associated with complex diseases

To increase statistical power to identify genes associated with complex traits, a number of transcriptome-wide association study (TWAS) methods have been proposed using gene expression as a mediating trait linking genetic variations and diseases. These methods first predict expression levels based o...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wei, Li, Mo, Zhang, Wenfeng, Zhou, Geyu, Wu, Xing, Wang, Jiawei, Lu, Qiongshi, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660930/
https://www.ncbi.nlm.nih.gov/pubmed/33137096
http://dx.doi.org/10.1371/journal.pcbi.1008315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660930/
https://www.ncbi.nlm.nih.gov/pubmed/33137096
http://dx.doi.org/10.1371/journal.pcbi.1008315

Ejemplares similares