Developmental and Functional Hair Cell-Like Cells Induced by Atoh1 Overexpression in the Adult Mammalian Cochlea In Vitro

Hair cells (HCs) in the mammalian cochleae cannot spontaneously regenerate once damaged, resulting in permanent hearing loss. It has been shown that Atoh1 overexpression induces hair cell-like cells (HCLCs) in the cochlea of newborn rodents, but this is hard to achieve in adult mammals. In this stud...

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Detalles Bibliográficos
Autores principales: Kong, Lingyi, Xin, Yuan, Chi, Fanglu, Chen, Jie, Yang, Juanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661126/
https://www.ncbi.nlm.nih.gov/pubmed/33204251
http://dx.doi.org/10.1155/2020/8885813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661126/
https://www.ncbi.nlm.nih.gov/pubmed/33204251
http://dx.doi.org/10.1155/2020/8885813

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