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Mechanism of Abnormal Chondrocyte Proliferation Induced by Piezo1-siRNA Exposed to Mechanical Stretch

OBJECTIVE: To investigate the effect of small interfering RNA targeting mechanosensitive ion channel protein Piezo1 (Piezo1-siRNA) on abnormal chondrocyte proliferation exposed to mechanical stretch. METHODS: Construct and screen effective Piezo1-siRNA sequences and explore an appropriate method to...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Leng, Ping, Li, Dawei, Gao, Huanshen, Li, Zhenghui, Li, Chenkai, Zhang, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661139/
https://www.ncbi.nlm.nih.gov/pubmed/33204718
http://dx.doi.org/10.1155/2020/8538463