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Serum keratin 19 (CYFRA21-1) links ductular reaction with portal hypertension and outcome of various advanced liver diseases

BACKGROUND: Keratins (Ks) represent tissue-specific proteins. K18 is produced in hepatocytes while K19, the most widely used ductular reaction (DR) marker, is found in cholangiocytes and hepatic progenitor cells. K18-based serum fragments are commonly used liver disease predictors, while K19-based s...

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Detalles Bibliográficos
Autores principales:	Hamesch, Karim, Guldiken, Nurdan, Aly, Mahmoud, Hüser, Norbert, Hartmann, Daniel, Rufat, Pierre, Ziol, Marianne, Remih, Katharina, Lurje, Georg, Scheiner, Bernhard, Trautwein, Christian, Mandorfer, Mattias, Reiberger, Thomas, Mueller, Sebastian, Bruns, Tony, Nahon, Pierre, Strnad, Pavel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661160/ https://www.ncbi.nlm.nih.gov/pubmed/33176798 http://dx.doi.org/10.1186/s12916-020-01784-7

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