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Leptin down-regulates KCC2 activity and controls chloride homeostasis in the neonatal rat hippocampus
The canonical physiological role of leptin is to regulate hunger and satiety acting on specific hypothalamic nuclei. Beyond this key metabolic function; leptin also regulates many aspects of development and functioning of neuronal hippocampal networks throughout life. Here we show that leptin contro...
Autores principales: | Dumon, Camille, Belaidouni, Yasmine, Diabira, Diabe, Appleyard, Suzanne M., Wayman, Gary A., Gaiarsa, Jean-Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661183/ https://www.ncbi.nlm.nih.gov/pubmed/33183317 http://dx.doi.org/10.1186/s13041-020-00689-z |
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