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Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta

PURPOSE: The Colon Cancer Screening Centre (CCSC) biorepository (Calgary, Canada) supports a wide range of research topics related to colorectal cancer (CRC) by collecting, and storing biospecimens (blood, urine, normal colon tissue) from consenting patient participants. Housing unique biospecimens...

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Autores principales: Hilsden, Robert J, Heitman, Steven J, Lamidi, Mubasiru, Diallo, Mamadou Dian, English, Janine, Town, Susanna, Cartwright, Shane, Maxwell, Courtney, McGillivray, Mary-Elizabeth, McGregor, Elizabeth, Barberio, Amanda, Pader, Joy, Brenner, Darren, Rabeneck, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661379/
https://www.ncbi.nlm.nih.gov/pubmed/33177135
http://dx.doi.org/10.1136/bmjopen-2020-038119
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author Hilsden, Robert J
Heitman, Steven J
Lamidi, Mubasiru
Diallo, Mamadou Dian
English, Janine
Town, Susanna
Cartwright, Shane
Maxwell, Courtney
McGillivray, Mary-Elizabeth
McGregor, Elizabeth
Barberio, Amanda
Pader, Joy
Brenner, Darren
Rabeneck, Linda
author_facet Hilsden, Robert J
Heitman, Steven J
Lamidi, Mubasiru
Diallo, Mamadou Dian
English, Janine
Town, Susanna
Cartwright, Shane
Maxwell, Courtney
McGillivray, Mary-Elizabeth
McGregor, Elizabeth
Barberio, Amanda
Pader, Joy
Brenner, Darren
Rabeneck, Linda
author_sort Hilsden, Robert J
collection PubMed
description PURPOSE: The Colon Cancer Screening Centre (CCSC) biorepository (Calgary, Canada) supports a wide range of research topics related to colorectal cancer (CRC) by collecting, and storing biospecimens (blood, urine, normal colon tissue) from consenting patient participants. Housing unique biospecimens along with detailed participant lifestyle and health history questionnaire data, the CCSC biorepository can support a variety of research related to CRC risk factors, biomarkers, genetic causes and more. PARTICIPANTS: Currently, 2292 average risk CRC patients have consented to participate in the CCSC cohort and have provided stored biospecimens. The collected samples and data provide important high-quality materials for research, discovery and evaluation related to CRC screening and carcinogenesis and is available for access by outside researchers. In addition to biological samples, the CCSC collects detailed patient information on their lifestyle, physical activity and dietary patterns through questionnaires at the time of their enrolment. FINDINGS TO DATE: The majority of participants (75%) are between 50 and 64 years of age. Women make up 46% (1055) of the cohort. Additional characteristics of the cohort included 44% reporting a body mass index of 25–30 kg/m(2) (overweight), 53% having never smoked tobacco and 13% having a family member with CRC. FUTURE PLANS: The CCSC cohort plans to include the recruitment of high risk CRC cohorts. High-risk participants would comprise patients with a positive faecal immunochemical test and family history of CRC.
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spelling pubmed-76613792020-11-20 Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta Hilsden, Robert J Heitman, Steven J Lamidi, Mubasiru Diallo, Mamadou Dian English, Janine Town, Susanna Cartwright, Shane Maxwell, Courtney McGillivray, Mary-Elizabeth McGregor, Elizabeth Barberio, Amanda Pader, Joy Brenner, Darren Rabeneck, Linda BMJ Open Oncology PURPOSE: The Colon Cancer Screening Centre (CCSC) biorepository (Calgary, Canada) supports a wide range of research topics related to colorectal cancer (CRC) by collecting, and storing biospecimens (blood, urine, normal colon tissue) from consenting patient participants. Housing unique biospecimens along with detailed participant lifestyle and health history questionnaire data, the CCSC biorepository can support a variety of research related to CRC risk factors, biomarkers, genetic causes and more. PARTICIPANTS: Currently, 2292 average risk CRC patients have consented to participate in the CCSC cohort and have provided stored biospecimens. The collected samples and data provide important high-quality materials for research, discovery and evaluation related to CRC screening and carcinogenesis and is available for access by outside researchers. In addition to biological samples, the CCSC collects detailed patient information on their lifestyle, physical activity and dietary patterns through questionnaires at the time of their enrolment. FINDINGS TO DATE: The majority of participants (75%) are between 50 and 64 years of age. Women make up 46% (1055) of the cohort. Additional characteristics of the cohort included 44% reporting a body mass index of 25–30 kg/m(2) (overweight), 53% having never smoked tobacco and 13% having a family member with CRC. FUTURE PLANS: The CCSC cohort plans to include the recruitment of high risk CRC cohorts. High-risk participants would comprise patients with a positive faecal immunochemical test and family history of CRC. BMJ Publishing Group 2020-11-11 /pmc/articles/PMC7661379/ /pubmed/33177135 http://dx.doi.org/10.1136/bmjopen-2020-038119 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Oncology
Hilsden, Robert J
Heitman, Steven J
Lamidi, Mubasiru
Diallo, Mamadou Dian
English, Janine
Town, Susanna
Cartwright, Shane
Maxwell, Courtney
McGillivray, Mary-Elizabeth
McGregor, Elizabeth
Barberio, Amanda
Pader, Joy
Brenner, Darren
Rabeneck, Linda
Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title_full Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title_fullStr Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title_full_unstemmed Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title_short Cohort profile: The Forzani & MacPhail Colon Cancer Screening Centre biorepository, Calgary, Alberta
title_sort cohort profile: the forzani & macphail colon cancer screening centre biorepository, calgary, alberta
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661379/
https://www.ncbi.nlm.nih.gov/pubmed/33177135
http://dx.doi.org/10.1136/bmjopen-2020-038119
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