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MSC encapsulation in alginate microcapsules prolongs survival after intra-articular injection, a longitudinal in vivo cell and bead integrity tracking study
Mesenchymal stem cells (MSC) are promising candidates for use as a biological therapeutic. Since locally injected MSC disappear within a few weeks, we hypothesize that efficacy of MSC can be enhanced by prolonging their presence. Previously, encapsulation in alginate was suggested as a suitable appr...
Autores principales: | Khatab, Sohrab, Leijs, Maarten J., van Buul, Gerben, Haeck, Joost, Kops, Nicole, Nieboer, Michael, Bos, P. Koen, Verhaar, Jan A. N., Bernsen, Monique, van Osch, Gerjo J. V. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661423/ https://www.ncbi.nlm.nih.gov/pubmed/32474743 http://dx.doi.org/10.1007/s10565-020-09532-6 |
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