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Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells

Mesodermal differentiation of induced pluripotent stem cells (iPSCs) in vitro and subsequent specification into mesodermal derivatives like chondrocytes is currently afflicted with a substantial cell loss that severely limits tissue yield. More knowledge on the key players regulating mesodermal diff...

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Detalles Bibliográficos
Autores principales: Kreuser, Ursula, Buchert, Justyna, Haase, Alexandra, Richter, Wiltrud, Diederichs, Solvig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661475/
https://www.ncbi.nlm.nih.gov/pubmed/33195222
http://dx.doi.org/10.3389/fcell.2020.581331