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Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells
Mesodermal differentiation of induced pluripotent stem cells (iPSCs) in vitro and subsequent specification into mesodermal derivatives like chondrocytes is currently afflicted with a substantial cell loss that severely limits tissue yield. More knowledge on the key players regulating mesodermal diff...
Autores principales: | Kreuser, Ursula, Buchert, Justyna, Haase, Alexandra, Richter, Wiltrud, Diederichs, Solvig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661475/ https://www.ncbi.nlm.nih.gov/pubmed/33195222 http://dx.doi.org/10.3389/fcell.2020.581331 |
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