Possible contribution of sialic acid to the enhanced tumor targeting efficiency of nanoparticles engineered with doxorubicin

Doxorubicin (DOX)-engineered poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) including phloretin (PHL) were designed and the feasible contribution of sialic acid (SA) to the improved tumor targeting and penetration capabilities was elucidated in lung adenocarcinoma models. DOX has been clin...

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Detalles Bibliográficos
Autores principales: Lee, Song Yi, Nam, Suyeong, Koo, Ja Seong, Kim, Sungyun, Yang, Mingyu, Jeong, Da In, Hwang, ChaeRim, Park, JiHye, Cho, Hyun-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661514/
https://www.ncbi.nlm.nih.gov/pubmed/33184416
http://dx.doi.org/10.1038/s41598-020-76778-9

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