Antibiofilm effects of N,O-acetals derived from 2-amino-1,4-naphthoquinone are associated with downregulation of important global virulence regulators in methicillin-resistant Staphylococcus aureus

Despite the existing antibiotics, antimicrobial resistance is a major challenge. Consequently, the development of new drugs remains in great demand. Quinones is part of a broad group of molecules that present antibacterial activity besides other biological properties. The main purpose of this study...

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Detalles Bibliográficos
Autores principales: Novais, Juliana Silva, Carvalho, Mariana Fernandes, Ramundo, Mariana Severo, Beltrame, Cristiana Ossaille, Geraldo, Reinaldo Barros, Jordão, Alessandro Kappel, Ferreira, Vítor Francisco, Castro, Helena Carla, Figueiredo, Agnes Marie Sá
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661526/
https://www.ncbi.nlm.nih.gov/pubmed/33184312
http://dx.doi.org/10.1038/s41598-020-76372-z

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