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Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq

Chemical-genetic interaction profiling in model organisms has proven powerful in providing insights into compound mechanism of action and gene function. However, identifying chemical-genetic interactions in mammalian systems has been limited to low-throughput or computational methods. Here, we devel...

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Detalles Bibliográficos
Autores principales:	Brockway, Sonia, Wang, Geng, Jackson, Jasen M., Amici, David R., Takagishi, Seesha R., Clutter, Matthew R., Bartom, Elizabeth T., Mendillo, Marc L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661543/ https://www.ncbi.nlm.nih.gov/pubmed/33184288 http://dx.doi.org/10.1038/s41467-020-19553-8

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