Cargando…

Opportunities for Antigen Discovery in Metastatic Breast Cancer

Immune checkpoint inhibitor-based immunotherapy (ICI) of breast cancer is currently efficacious in a fraction of triple negative breast cancers (TNBC) as these cancers generally carry high tumor mutation burden (TMB) and show increased tumor infiltration by CD8(+) T cells. However, most estrogen rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sood, Ashwani K., Nemeth, Michael, Wang, Jianmin, Wu, Yun, Gandhi, Shipra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661635/ https://www.ncbi.nlm.nih.gov/pubmed/33193348 http://dx.doi.org/10.3389/fimmu.2020.570049

Ejemplares similares

Significance of the Genomic Landscape of a De Novo Endocrine-Resistant Metastatic Hormone Receptor–Positive Breast Cancer
por: Sarma, Maithreyi, et al.
Publicado: (2020)

Antigen-Specific Treg Therapy in Type 1 Diabetes – Challenges and Opportunities
por: Serr, Isabelle, et al.
Publicado: (2021)

Massively-multiplexed epitope mapping techniques for viral antigen discovery
por: Hu, Diya, et al.
Publicado: (2023)

Chimeric Antigen Receptor (CAR)-T Cell Immunotherapy Against Thoracic Malignancies: Challenges and Opportunities
por: Chen, Long, et al.
Publicado: (2022)

Antibodies Against Conserved Antigens Provide Opportunities for Reform in Influenza Vaccine Design
por: Kaminski, Denise A., et al.
Publicado: (2011)

Clinical outcomes of de novo metastatic HER2-low breast cancer: a National Cancer Database Analysis
por: Jiang, Changchuan, et al.
Publicado: (2022)

Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery
por: Dalsass, Mattia, et al.
Publicado: (2019)

Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis
por: Pearson, Mark S., et al.
Publicado: (2021)

Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy
por: Das, Shipra, et al.
Publicado: (2023)

Bacterial Vaccine Antigen Discovery in the Reverse Vaccinology 2.0 Era: Progress and Challenges
por: Bidmos, Fadil A., et al.
Publicado: (2018)

Immune Signatures and Survival of Patients With Metastatic Melanoma, Renal Cancer, and Breast Cancer
por: Wistuba-Hamprecht, Kilian, et al.
Publicado: (2020)

Novel Biomarkers to Guide Immunotherapy De-Escalation in the Neoadjuvant Setting in Triple-Negative Breast Cancer
por: Gandhi, Shipra
Publicado: (2023)

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?
por: Huber, Anne, et al.
Publicado: (2018)

Protein-Based Immunome Wide Association Studies (PIWAS) for the Discovery of Significant Disease-Associated Antigens
por: Haynes, Winston A., et al.
Publicado: (2021)

The landscape of chimeric antigen receptor T cell therapy in breast cancer: Perspectives and outlook
por: Zhang, Hao, et al.
Publicado: (2022)

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens
por: Fuchs, Kyra J., et al.
Publicado: (2020)

Cutting edges and therapeutic opportunities on tumor-associated macrophages in lung cancer
por: Hu, Qin, et al.
Publicado: (2022)

Teleost fish IgM(+) plasma-like cells possess IgM-secreting, phagocytic, and antigen-presenting capacities
por: Wu, Liting, et al.
Publicado: (2022)

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer
por: Mukhopadhyay, Alka, et al.
Publicado: (2013)

Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy
por: Crispell, Gary, et al.
Publicado: (2019)

A Rare Case of Missing Primary in Metastatic Renal Cell Carcinoma
por: Kapoor, Ankita, et al.
Publicado: (2020)

Effects of Combinatorial Ubiquitinated Protein-Based Nanovaccine and STING Agonist in Mice With Drug-Resistant and Metastatic Breast Cancer
por: Huang, Fang, et al.
Publicado: (2021)

Association of the Microbiota and Pancreatic Cancer: Opportunities and Limitations
por: Chen, Zhou, et al.
Publicado: (2022)

T cell immunotherapy for cervical cancer: challenges and opportunities
por: Yu, Lingfeng, et al.
Publicado: (2023)

Alveolar macrophages in lung cancer: opportunities and challenges
por: Chang, Cheng-Yen, et al.
Publicado: (2023)

Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery
por: Walker, Kayleigh, et al.
Publicado: (2023)

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer
por: Steenbrugge, Jonas, et al.
Publicado: (2019)

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
por: Weidanz, Jon A., et al.
Publicado: (2015)

Therapeutic Opportunities of Interleukin-33 in the Central Nervous System
por: Sun, Yun, et al.
Publicado: (2021)

Novel lipid antigens for NKT cells in cancer
por: Lee, Michael S., et al.
Publicado: (2023)

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies
por: Harris, Katherine E., et al.
Publicado: (2018)

Neutrophil: A New Player in Metastatic Cancers
por: Wu, Mengyue, et al.
Publicado: (2020)

HIV-Infected Patients Developing Tuberculosis Disease Show Early Changes in the Immune Response to Novel Mycobacterium tuberculosis Antigens
por: Meier, Noemi Rebecca, et al.
Publicado: (2021)

Case Report: Long-Term Response to Pembrolizumab Combined With Endocrine Therapy in Metastatic Breast Cancer Patients With Hormone Receptor Expression
por: Wu, Dingyong, et al.
Publicado: (2021)

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer
por: Kitamura, Takanori, et al.
Publicado: (2018)

Corrigendum: Alveolar macrophages in lung cancer: opportunities and challenges
por: Chang, Cheng-Yen, et al.
Publicado: (2023)

Real world outcomes with alpelisib in metastatic hormone receptor-positive breast cancer patients: A single institution experience
por: Alaklabi, Sabah, et al.
Publicado: (2022)

Neoadjuvant Chemotherapy for Breast Cancer: Past, Present, and Future
por: Asaoka, Mariko, et al.
Publicado: (2020)

Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer
por: Liubomirski, Yulia, et al.
Publicado: (2019)

IFNγ Modulates the Immunopeptidome of Triple Negative Breast Cancer Cells by Enhancing and Diversifying Antigen Processing and Presentation
por: Goncalves, Gabriel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1l90hbs4ap8su7ga3nkorl8cd8