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Sulforaphane Promotes Dendritic Cell Stimulatory Capacity Through Modulation of Regulatory Molecules, JAK/STAT3- and MicroRNA-Signaling

INTRODUCTION: The broccoli isothiocyanate sulforaphane was shown to inhibit inflammation and tumor progression, also in pancreatic cancer, while its effect on tumor immunity is poorly understood. We investigated the immunoregulatory effect of sulforaphane on human dendritic cells alone and in presen...

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Detalles Bibliográficos
Autores principales: Wang, Yangyi, Petrikova, Emilia, Gross, Wolfgang, Sticht, Carsten, Gretz, Norbert, Herr, Ingrid, Karakhanova, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661638/
https://www.ncbi.nlm.nih.gov/pubmed/33193420
http://dx.doi.org/10.3389/fimmu.2020.589818