The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update

Cardiac amyloidosis (CA) is a unique disease entity involving an infiltrative process, typically resulting in a restrictive cardiomyopathy with diastolic heart failure that ultimately progresses to systolic heart failure. The two most common subtypes are light-chain and transthyretin amyloidosis. Ea...

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Autores principales: Khanna, Shaun, Wen, Ivy, Bhat, Aditya, Chen, Henry H. L., Gan, Gary C. H., Pathan, Faraz, Tan, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661689/
https://www.ncbi.nlm.nih.gov/pubmed/33195479
http://dx.doi.org/10.3389/fcvm.2020.590557
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author Khanna, Shaun
Wen, Ivy
Bhat, Aditya
Chen, Henry H. L.
Gan, Gary C. H.
Pathan, Faraz
Tan, Timothy C.
author_facet Khanna, Shaun
Wen, Ivy
Bhat, Aditya
Chen, Henry H. L.
Gan, Gary C. H.
Pathan, Faraz
Tan, Timothy C.
author_sort Khanna, Shaun
collection PubMed
description Cardiac amyloidosis (CA) is a unique disease entity involving an infiltrative process, typically resulting in a restrictive cardiomyopathy with diastolic heart failure that ultimately progresses to systolic heart failure. The two most common subtypes are light-chain and transthyretin amyloidosis. Early diagnosis of this disease entity, especially light-chain CA subtype, is crucial, as it portends a poorer prognosis. This review focuses on the clinical utility of the various imaging modalities in the diagnosis and differentiation of CA subtypes. This review also aims to highlight the key advances in each of the imaging modalities in the diagnosis and prognostication of CA.
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spelling pubmed-76616892020-11-13 The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update Khanna, Shaun Wen, Ivy Bhat, Aditya Chen, Henry H. L. Gan, Gary C. H. Pathan, Faraz Tan, Timothy C. Front Cardiovasc Med Cardiovascular Medicine Cardiac amyloidosis (CA) is a unique disease entity involving an infiltrative process, typically resulting in a restrictive cardiomyopathy with diastolic heart failure that ultimately progresses to systolic heart failure. The two most common subtypes are light-chain and transthyretin amyloidosis. Early diagnosis of this disease entity, especially light-chain CA subtype, is crucial, as it portends a poorer prognosis. This review focuses on the clinical utility of the various imaging modalities in the diagnosis and differentiation of CA subtypes. This review also aims to highlight the key advances in each of the imaging modalities in the diagnosis and prognostication of CA. Frontiers Media S.A. 2020-10-30 /pmc/articles/PMC7661689/ /pubmed/33195479 http://dx.doi.org/10.3389/fcvm.2020.590557 Text en Copyright © 2020 Khanna, Wen, Bhat, Chen, Gan, Pathan and Tan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Khanna, Shaun
Wen, Ivy
Bhat, Aditya
Chen, Henry H. L.
Gan, Gary C. H.
Pathan, Faraz
Tan, Timothy C.
The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title_full The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title_fullStr The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title_full_unstemmed The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title_short The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update
title_sort role of multi-modality imaging in the diagnosis of cardiac amyloidosis: a focused update
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661689/
https://www.ncbi.nlm.nih.gov/pubmed/33195479
http://dx.doi.org/10.3389/fcvm.2020.590557
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