Anti-High Mobility Group Box 1 Neutralizing-Antibody Ameliorates Dextran Sodium Sulfate Colitis in Mice

High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein in mammals. When released into the extracellular space, it acts as a damage-associated molecular pattern. This study investigates whether increased HMGB1 levels are found in the intestinal mucosa of ulcerative colitis (UC) patients, a...

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Detalles Bibliográficos
Autores principales: Chen, Liping, Li, Junhua, Ye, Zhenghao, Sun, Binghua, Wang, Lu, Chen, Yu, Han, Jian, Yu, Meiping, Wang, Ying, Zhou, Qi, Seidler, Ursula, Tian, De’an, Xiao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661783/
https://www.ncbi.nlm.nih.gov/pubmed/33193406
http://dx.doi.org/10.3389/fimmu.2020.585094

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