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The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

It has been previously found that the blockade of metabotropic glutamate receptor type 5 (mGluR5) protects against hepatic ischemia/reperfusion injury and acetaminophen toxicity. The role of mGluR5 in NAFLD has not yet been elucidated. Here, we evaluated the effects of mGluR5 blockade in an in vitro...

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Detalles Bibliográficos
Autores principales: Ferrigno, Andrea, Berardo, Clarissa, Di Pasqua, Laura Giuseppina, Cagna, Marta, Siciliano, Veronica, Richelmi, Plinio, Vairetti, Mariapia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662107/
https://www.ncbi.nlm.nih.gov/pubmed/33207858
http://dx.doi.org/10.4081/ejh.2020.3175

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