Profiling of Histone Modifications Reveals Epigenomic Dynamics During Abdominal Aortic Aneurysm Formation in Mouse Models

Introduction: Abdominal aortic aneurysms (AAA) are characterized by localized inflammation, extracellular matrix degradation, and apoptosis of smooth muscle cells, which together lead to progressive and irreversible aortic dilation. Major risk factors for AAA include smoking and aging, both of which...

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Detalles Bibliográficos
Autores principales: Greenway, Jacob, Gilreath, Nicole, Patel, Sagar, Horimatsu, Tetsuo, Moses, Mary, Kim, David, Reid, Lauren, Ogbi, Mourad, Shi, Yang, Lu, Xin-Yun, Shukla, Mrinal, Lee, Richard, Huo, Yuqing, Young, Lufei, Kim, Ha Won, Weintraub, Neal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662126/
https://www.ncbi.nlm.nih.gov/pubmed/33195484
http://dx.doi.org/10.3389/fcvm.2020.595011

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