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Transcriptional Programs Driving Shear Stress-Induced Differentiation of Kidney Proximal Tubule Cells in Culture

Cultured cell models are an essential complement to dissecting kidney proximal tubule (PT) function in health and disease but do not fully recapitulate key features of this nephron segment. We recently determined that culture of opossum kidney (OK) cells under continuous orbital shear stress (OSS) s...

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Detalles Bibliográficos
Autores principales: Park, Hyun Jung, Fan, Zhenjiang, Bai, Yulong, Ren, Qidong, Rbaibi, Youssef, Long, Kimberly R., Gliozzi, Megan L., Rittenhouse, Natalie, Locker, Joseph D., Poholek, Amanda C., Weisz, Ora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662153/
https://www.ncbi.nlm.nih.gov/pubmed/33192601
http://dx.doi.org/10.3389/fphys.2020.587358