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Discovery of Novel Indolealkylpiperazine Derivatives as Potent 5-HT(1A) Receptor Agonists for the Potential Future Treatment of Depression

Depression is a severe psychiatric disorder that affects over 100 million people worldwide. 5-HT(1A) receptor agonists have been implicated in the treatment of a variety of central nervous system diseases, especially depression. In this study, based on FW01, a selective potent 5-HT(1A)R agonist disc...

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Detalles Bibliográficos
Autores principales: Zhu, Chen, Li, Xinwei, Peng, Weiqing, Fu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662226/
https://www.ncbi.nlm.nih.gov/pubmed/33139658
http://dx.doi.org/10.3390/molecules25215078