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Molecular Aspects of Mycotoxins—A Serious Problem for Human Health
Mycotoxins are toxic fungal secondary metabolities formed by a variety of fungi (moulds) species. Hundreds of potentially toxic mycotoxins have been already identified and are considered a serious problem in agriculture, animal husbandry, and public health. A large number of food-related products an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662353/ https://www.ncbi.nlm.nih.gov/pubmed/33142955 http://dx.doi.org/10.3390/ijms21218187 |
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author | Janik, Edyta Niemcewicz, Marcin Ceremuga, Michal Stela, Maksymilian Saluk-Bijak, Joanna Siadkowski, Adrian Bijak, Michal |
author_facet | Janik, Edyta Niemcewicz, Marcin Ceremuga, Michal Stela, Maksymilian Saluk-Bijak, Joanna Siadkowski, Adrian Bijak, Michal |
author_sort | Janik, Edyta |
collection | PubMed |
description | Mycotoxins are toxic fungal secondary metabolities formed by a variety of fungi (moulds) species. Hundreds of potentially toxic mycotoxins have been already identified and are considered a serious problem in agriculture, animal husbandry, and public health. A large number of food-related products and beverages are yearly contaminated by mycotoxins, resulting in economic welfare losses. Mycotoxin indoor environment contamination is a global problem especially in less technologically developed countries. There is an ongoing effort in prevention of mould growth in the field and decontamination of contaminated food and feed in order to protect human and animal health. It should be emphasized that the mycotoxins production by fungi (moulds) species is unavoidable and that they are more toxic than pesticides. Human and animals are exposed to mycotoxin via food, inhalation, or contact which can result in many building-related illnesses including kidney and neurological diseases and cancer. In this review, we described in detail the molecular aspects of main representatives of mycotoxins, which are serious problems for global health, such as aflatoxins, ochratoxin A, T-2 toxin, deoxynivalenol, patulin, and zearalenone. |
format | Online Article Text |
id | pubmed-7662353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76623532020-11-14 Molecular Aspects of Mycotoxins—A Serious Problem for Human Health Janik, Edyta Niemcewicz, Marcin Ceremuga, Michal Stela, Maksymilian Saluk-Bijak, Joanna Siadkowski, Adrian Bijak, Michal Int J Mol Sci Review Mycotoxins are toxic fungal secondary metabolities formed by a variety of fungi (moulds) species. Hundreds of potentially toxic mycotoxins have been already identified and are considered a serious problem in agriculture, animal husbandry, and public health. A large number of food-related products and beverages are yearly contaminated by mycotoxins, resulting in economic welfare losses. Mycotoxin indoor environment contamination is a global problem especially in less technologically developed countries. There is an ongoing effort in prevention of mould growth in the field and decontamination of contaminated food and feed in order to protect human and animal health. It should be emphasized that the mycotoxins production by fungi (moulds) species is unavoidable and that they are more toxic than pesticides. Human and animals are exposed to mycotoxin via food, inhalation, or contact which can result in many building-related illnesses including kidney and neurological diseases and cancer. In this review, we described in detail the molecular aspects of main representatives of mycotoxins, which are serious problems for global health, such as aflatoxins, ochratoxin A, T-2 toxin, deoxynivalenol, patulin, and zearalenone. MDPI 2020-10-31 /pmc/articles/PMC7662353/ /pubmed/33142955 http://dx.doi.org/10.3390/ijms21218187 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Janik, Edyta Niemcewicz, Marcin Ceremuga, Michal Stela, Maksymilian Saluk-Bijak, Joanna Siadkowski, Adrian Bijak, Michal Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title | Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title_full | Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title_fullStr | Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title_full_unstemmed | Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title_short | Molecular Aspects of Mycotoxins—A Serious Problem for Human Health |
title_sort | molecular aspects of mycotoxins—a serious problem for human health |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662353/ https://www.ncbi.nlm.nih.gov/pubmed/33142955 http://dx.doi.org/10.3390/ijms21218187 |
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