Cargando…

Sarcopenia Induced by Chronic Liver Disease in Mice Requires the Expression of the Bile Acids Membrane Receptor TGR5

Sarcopenia is a condition of muscle dysfunction, commonly associated with chronic liver disease (CLD), characterized by a decline in muscle strength, the activation of the ubiquitin-proteasome system (UPS), and oxidative stress. We recently described a murine model of CLD-induced sarcopenia by intak...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abrigo, Johanna, Campos, Fabián, Gonzalez, Francisco, Aguirre, Francisco, Gonzalez, Andrea, Huerta-Salgado, Camila, Conejeros, Sabrina, Simon, Felipe, Arrese, Marco, Cabrera, Daniel, Elorza, Alvaro A., Cabello-Verrugio, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662491/ https://www.ncbi.nlm.nih.gov/pubmed/33113850 http://dx.doi.org/10.3390/ijms21217922

Ejemplares similares

Protective Effect of Angiotensin 1–7 on Sarcopenia Induced by Chronic Liver Disease in Mice
por: Aguirre, Francisco, et al.
Publicado: (2020)

Bile Acids Induce Alterations in Mitochondrial Function in Skeletal Muscle Fibers
por: Abrigo, Johanna, et al.
Publicado: (2022)

Angiotensin (1-7) Decreases Myostatin-Induced NF-κB Signaling and Skeletal Muscle Atrophy
por: Aravena, Javier, et al.
Publicado: (2020)

Impact of exercise training on the sarcopenia criteria in non-alcoholic fatty liver disease: a systematic review and meta-analysis
por: Gonzalez, Andrea, et al.
Publicado: (2021)

Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia
por: Ábrigo, Johanna, et al.
Publicado: (2018)

Role of Oxidative Stress in Hepatic and Extrahepatic Dysfunctions during Nonalcoholic Fatty Liver Disease (NAFLD)
por: Gonzalez, Andrea, et al.
Publicado: (2020)

Intensive care unit-acquired weakness: A review from molecular mechanisms to its impact in COVID-2019
por: González, Andrea, et al.
Publicado: (2022)

Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux
por: Orozco-Aguilar, Josué, et al.
Publicado: (2023)

Cholic and deoxycholic acids induce mitochondrial dysfunction, impaired biogenesis and autophagic flux in skeletal muscle cells
por: Abrigo, Johanna, et al.
Publicado: (2023)

Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease: Beneficial Hepatic and Systemic Effects of Hormone Supplementation
por: Cabrera, Daniel, et al.
Publicado: (2018)

Redox-Dependent Effects in the Physiopathological Role of Bile Acids
por: Orozco-Aguilar, Josué, et al.
Publicado: (2021)

Central anorexigenic actions of bile acids are mediated by TGR5
por: Perino, Alessia, et al.
Publicado: (2021)

High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis
por: Abrigo, Johanna, et al.
Publicado: (2016)

Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways
por: Baptissart, Marine, et al.
Publicado: (2018)

The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?
por: Qi, Youchao, et al.
Publicado: (2022)

Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
por: Hov, Johannes R., et al.
Publicado: (2010)

The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice
por: Márquez-Miranda, Valeria, et al.
Publicado: (2017)

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas
por: Morales, María Gabriela, et al.
Publicado: (2016)

TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload
por: Bidault-Jourdainne, Valeska, et al.
Publicado: (2020)

Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration
por: Keitel, Verena, et al.
Publicado: (2014)

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR
por: Jadhav, Kavita, et al.
Publicado: (2018)

Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists
por: Miyata, Sachiho, et al.
Publicado: (2021)

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction
por: Leonhardt, Julia, et al.
Publicado: (2021)

Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
por: Trammell, Samuel A. J., et al.
Publicado: (2020)

Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle
por: Rivera, Juan Carlos, et al.
Publicado: (2020)

The Critical Role of Oxidative Stress in Sarcopenic Obesity
por: Gonzalez, Andrea, et al.
Publicado: (2021)

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2011)

Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
por: Echeverría, César, et al.
Publicado: (2013)

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic syndrome
por: Stepanov, Vanesa, et al.
Publicado: (2012)

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
por: Cipriani, Sabrina, et al.
Publicado: (2013)

GPBAR1/TGR5 Mediates Bile Acid-Induced Cytokine Expression in Murine Kupffer Cells
por: Lou, Guiyu, et al.
Publicado: (2014)

Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia
por: Chen, Min-Chan, et al.
Publicado: (2016)

Cryo-EM structure of activated bile acids receptor TGR5 in complex with stimulatory G protein
por: Chen, Geng, et al.
Publicado: (2020)

Activation of the bile acid receptors TGR5 and FXR in the spinal dorsal horn alleviates neuropathic pain
por: Wu, Yuning, et al.
Publicado: (2023)

Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5
por: Ladurner, Angela, et al.
Publicado: (2017)

Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5
por: Qi, Youchao, et al.
Publicado: (2021)

Evaluation of G-Protein-Coupled Bile Acid Receptor 1 (TGR5) Levels in Intrahepatic Cholestasis of Pregnancy
por: Irak, Kader, et al.
Publicado: (2021)

Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5
por: Chen, Xiaosong, et al.
Publicado: (2015)

TGR5-HNF4α axis contributes to bile acid-induced gastric intestinal metaplasia markers expression
por: Ni, Zhen, et al.
Publicado: (2020)

The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver
por: Klindt, Caroline, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ucnmc1ml7r8b875ukpkr5mv2il