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Relationship of 2D Affinity to T Cell Functional Outcomes
T cells are critical for a functioning adaptive immune response and a strong correlation exists between T cell responses and T cell receptor (TCR): peptide-loaded MHC (pMHC) binding. Studies that utilize pMHC tetramer, multimers, and assays of three-dimensional (3D) affinity have provided advancemen...
Autores principales: | Kolawole, Elizabeth M., Lamb, Tracey J., Evavold, Brian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662510/ https://www.ncbi.nlm.nih.gov/pubmed/33120989 http://dx.doi.org/10.3390/ijms21217969 |
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