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Relationship of 2D Affinity to T Cell Functional Outcomes

T cells are critical for a functioning adaptive immune response and a strong correlation exists between T cell responses and T cell receptor (TCR): peptide-loaded MHC (pMHC) binding. Studies that utilize pMHC tetramer, multimers, and assays of three-dimensional (3D) affinity have provided advancemen...

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Detalles Bibliográficos
Autores principales: Kolawole, Elizabeth M., Lamb, Tracey J., Evavold, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662510/
https://www.ncbi.nlm.nih.gov/pubmed/33120989
http://dx.doi.org/10.3390/ijms21217969

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