A Novel Type-I Interferon Family, Bovine Interferon-Chi, Is Involved in Positive-Feedback Regulation of Interferon Production

Interferon-chi (IFN-χ) is a type of function-unknown IFN. IFN-χ in bovines (BoIFN-χ) has evolved as a multigene family. This family comprises four IFN-χ subtypes, two of which are functional genes, which we demonstrated to (i) have antiviral and antiproliferative activities, (ii) be highly sensitive...

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Detalles Bibliográficos
Autores principales: Guo, Yongli, Song, Zhifeng, Li, Chenfeng, Yu, Yueyang, Dai, Haiyue, Luo, Xiuxin, Wang, Yujiao, Wang, Junwei, Gao, Mingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662560/
https://www.ncbi.nlm.nih.gov/pubmed/33193303
http://dx.doi.org/10.3389/fimmu.2020.528854

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