Cargando…

Protective Role of St. John’s Wort and Its Components Hyperforin and Hypericin against Diabetes through Inhibition of Inflammatory Signaling: Evidence from In Vitro and In Vivo Studies

Diabetes mellitus is a very common chronic disease with progressively increasing prevalence. Besides the well-known autoimmune and inflammatory pathogenesis of type 1 diabetes, in many people, metabolic changes and inappropriate lifestyle favor a subtle chronic inflammatory state that contributes to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Novelli, Michela, Masiello, Pellegrino, Beffy, Pascale, Menegazzi, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662691/ https://www.ncbi.nlm.nih.gov/pubmed/33143088 http://dx.doi.org/10.3390/ijms21218108

Ejemplares similares

St. John’s wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity
por: Novelli, Michela, et al.
Publicado: (2013)

Anti-Tumor Activity of Hypericum perforatum L. and Hyperforin through Modulation of Inflammatory Signaling, ROS Generation and Proton Dynamics
por: Menegazzi, Marta, et al.
Publicado: (2020)

Optimization of Light Intensity, Temperature, and Nutrients to Enhance the Bioactive Content of Hyperforin and Rutin in St. John’s Wort
por: Kuo, Chia-Hung, et al.
Publicado: (2020)

Transplacental passage of hyperforin, hypericin, and valerenic acid
por: Spiess, Deborah, et al.
Publicado: (2023)

Discovery of key regulators of dark gland development and hypericin biosynthesis in St. John's Wort (Hypericum perforatum)
por: Rizzo, Paride, et al.
Publicado: (2019)

Analysis of hyperforin (St. John’s wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs
por: El Hamdaoui, Yamina, et al.
Publicado: (2022)

No Clinically Relevant Interactions of St. John's Wort Extract Ze 117 Low in Hyperforin With Cytochrome P450 Enzymes and P‐glycoprotein
por: Zahner, Catherine, et al.
Publicado: (2019)

Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo
por: Koeberle, Andreas, et al.
Publicado: (2011)

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death
por: Kleemann, Britta, et al.
Publicado: (2014)

St. John’s Wort-Induced Supraventricular Tachycardia
por: Fisher, Kristy A, et al.
Publicado: (2021)

St. John's Wort Has Metabolically Favorable Effects on Adipocytes In Vivo
por: Fuller, Scott, et al.
Publicado: (2014)

Are the St John’s wort Hyp-1 superstructures different?
por: Lovelace, Jeffrey J., et al.
Publicado: (2021)

St. John's Wort usage in treating of perinatal depression
por: Zepeda, Rossana C., et al.
Publicado: (2023)

Clinical relevance of St. John's wort drug interactions revisited
por: Nicolussi, Simon, et al.
Publicado: (2020)

Cytological and Biochemical Effects of St. John’s Wort Supplement (A Complex Mixture of St. John’s Wort, Rosemary and Spirulina) on Somatic and Germ Cells of Swiss Albino Mice
por: Aleisa, A. M.
Publicado: (2008)

Black Cohosh and St. John's Wort (GYNO-Plus®) for Climacteric Symptoms
por: Chung, Da-Jung, et al.
Publicado: (2007)

A systematic review of St. John’s wort for major depressive disorder
por: Apaydin, Eric A., et al.
Publicado: (2016)

Effects of St John's Wort (Hypericum perforatum L.) Extracts on Epileptogenesis
por: Ivetic, Vesna, et al.
Publicado: (2011)

Estimation of Dermatological Application of Creams with St. John’s Wort Oil Extracts
por: Arsić, Ivana, et al.
Publicado: (2011)

Advantages and Disadvantages of Using St. John's Wort as a Treatment for Depression
por: Canenguez Benitez, Johanna S, et al.
Publicado: (2022)

Clinically relevant safety issues associated with St. John's wort product labels
por: Clauson, Kevin A, et al.
Publicado: (2008)

St. John’s Wort (Hypericum perforatum) Products – How Variable Is the Primary Material?
por: Scotti, Francesca, et al.
Publicado: (2019)

St John’s wort (Hypericum perforatum)-induced psychosis: a case report
por: Ferrara, Maria, et al.
Publicado: (2017)

A Systematic Review of the Use of St. John’s Wort for Smoking Cessation in Adults
por: Walia, Namrata, et al.
Publicado: (2021)

Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane
por: Majerník, Martin, et al.
Publicado: (2019)

Partial Deletion of eNOS Gene Causes Hyperinsulinemic State, Unbalance of Cardiac Insulin Signaling Pathways and Coronary Dysfunction Independently of High Fat Diet
por: Vecoli, Cecilia, et al.
Publicado: (2014)

Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort
por: Guo, Yi, et al.
Publicado: (2021)

Bigel Formulations of Nanoencapsulated St. John’s Wort Extract—An Approach for Enhanced Wound Healing
por: Sotirova, Yoana, et al.
Publicado: (2023)

Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John’s Wort Plant Constituents and Their Potential for the Treatment of Depression
por: Salawi, Ahmad, et al.
Publicado: (2023)

Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets
por: Martino, Luisa, et al.
Publicado: (2012)

The Chemical and Antibacterial Evaluation of St. John's Wort Oil Macerates Used in Kosovar Traditional Medicine
por: Lyles, James T., et al.
Publicado: (2017)

Effects of circadian clock and light on melatonin concentration in Hypericum perforatum L. (St. John’s Wort)
por: Chung, Ming-Hsiu, et al.
Publicado: (2020)

Antiproliferative Effects of St. John’s Wort, Its Derivatives, and Other Hypericum Species in Hematologic Malignancies
por: Allegra, Alessandro, et al.
Publicado: (2020)

Impact of St. John’s wort extract Ze 117 on stress induced changes in the lipidome of PBMC
por: Bussmann, Hendrik, et al.
Publicado: (2023)

DNA Authentication of St John’s Wort (Hypericum perforatum L.) Commercial Products Targeting the ITS Region
por: Howard, Caroline, et al.
Publicado: (2019)

From St. John’s wort to tomato and from Rhodiola to cranberry: A review of phytotherapy and some examples
por: Weixlbaumer, Verena, et al.
Publicado: (2020)

Neurotrophic, Cytoprotective, and Anti-inflammatory Effects of St. John's Wort Extract on Differentiated Mouse Hippocampal HT-22 Neurons
por: Bonaterra, Gabriel A., et al.
Publicado: (2018)

Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic Markers
por: Cardile, Alessia, et al.
Publicado: (2023)

Effect of St. John's Wort (Hypericum perforatum) treatment on restraint stress-induced behavioral and biochemical alteration in mice
por: Kumar, Anil, et al.
Publicado: (2010)

Effect of St. John's Wort (Hypericum perforatum) on obesity, lipid metabolism and uterine epithelial proliferation in ovariectomized rats
por: You, Mi-Kyoung, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jlhsgdet13f71p2mc9707ib94c