Kynurenine Promotes RANKL-Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway

There is increasing evidence of the involvement of the tryptophan metabolite kynurenine (KYN) in disrupting osteogenesis and contributing to aging-related bone loss. Here, we show that KYN has an effect on bone resorption by increasing osteoclastogenesis. We have previously reported that in vivo tre...

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Detalles Bibliográficos
Autores principales: Eisa, Nada H., Reddy, Sakamuri V., Elmansi, Ahmed M., Kondrikova, Galina, Kondrikov, Dmitry, Shi, Xing-Ming, Novince, Chad M., Hamrick, Mark W., McGee-Lawrence, Meghan E., Isales, Carlos M., Fulzele, Sadanand, Hill, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662708/
https://www.ncbi.nlm.nih.gov/pubmed/33114603
http://dx.doi.org/10.3390/ijms21217931

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