Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A

Merkel cell carcinomas (MCCs) are rare, aggressive, cutaneous neuroendocrine tumours, approximately 80% of which are caused by the genomic integration of Merkel cell polyomavirus (MCPyV). MCPyV-positive MCCs carry poor prognosis in approximately 70% of cases, highlighting the need for greater unders...

Descripción completa

Detalles Bibliográficos
Autores principales: Guadagni, Stefano, Farina, Antonietta Rosella, Cappabianca, Lucia Annamaria, Sebastiano, Michela, Maccarone, Rita, Zelli, Veronica, Clementi, Marco, Chiominto, Alessandro, Bruera, Gemma, Ricevuto, Enrico, Fiorentini, Giammaria, Sarti, Donatella, Mackay, Andrew Reay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662965/
https://www.ncbi.nlm.nih.gov/pubmed/33153070
http://dx.doi.org/10.3390/ijms21218222

Ejemplares similares

Ejemplares similares