Cyclic Peptide-Based Biologics Regulating HGF-MET

Using a random non-standard peptide integrated discovery system, we obtained cyclic peptides that bind to hepatocyte growth factor (HGF) or mesenchymal-epithelial transition factor. (MET) HGF-inhibitory peptide-8 (HiP-8) selectively bound to two-chain active HGF, but not to single-chain precursor HG...

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Detalles Bibliográficos
Autores principales: Sato, Hiroki, Imamura, Ryu, Suga, Hiroaki, Matsumoto, Kunio, Sakai, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662982/
https://www.ncbi.nlm.nih.gov/pubmed/33121208
http://dx.doi.org/10.3390/ijms21217977

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