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The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer

The TRIOBP (TRIO and F-actin Binding Protein) gene encodes multiple proteins, which together play crucial roles in modulating the assembly of the actin cytoskeleton. Splicing of the TRIOBP gene is complex, with the two most studied TRIOBP protein isoforms sharing no overlapping amino acid sequence w...

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Detalles Bibliográficos
Autores principales: Zaharija, Beti, Samardžija, Bobana, Bradshaw, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663296/
https://www.ncbi.nlm.nih.gov/pubmed/33121024
http://dx.doi.org/10.3390/molecules25214967

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