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Toxicant-Induced Metabolic Alterations in Lipid and Amino Acid Pathways Are Predictive of Acute Liver Toxicity in Rats
Liver disease and disorders associated with aberrant hepatocyte metabolism can be initiated via drug and environmental toxicant exposures. In this study, we tested the hypothesis that gene and metabolic profiling can reveal commonalities in liver response to different toxicants and provide the capab...
Autores principales: | Pannala, Venkat R., Estes, Shanea K., Rahim, Mohsin, Trenary, Irina, O’Brien, Tracy P., Shiota, Chiyo, Printz, Richard L., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663358/ https://www.ncbi.nlm.nih.gov/pubmed/33158035 http://dx.doi.org/10.3390/ijms21218250 |
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