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Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts

Keloid is a representative chronic fibroproliferative condition that occurs after tissue injury. Emerging evidence showed that activation of NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome is involved in the pro-inflammatory response in injured tissues. However, the role of NLR...

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Detalles Bibliográficos
Autores principales: Lee, Seongju, Kim, Sun Kyeon, Park, Hyungsun, Lee, Yu Jin, Park, Song Hee, Lee, Kyung Jae, Lee, Dong Geon, Kang, Hoon, Kim, Jung Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663397/
https://www.ncbi.nlm.nih.gov/pubmed/33126764
http://dx.doi.org/10.3390/ijms21218050