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Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts
Keloid is a representative chronic fibroproliferative condition that occurs after tissue injury. Emerging evidence showed that activation of NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome is involved in the pro-inflammatory response in injured tissues. However, the role of NLR...
Autores principales: | Lee, Seongju, Kim, Sun Kyeon, Park, Hyungsun, Lee, Yu Jin, Park, Song Hee, Lee, Kyung Jae, Lee, Dong Geon, Kang, Hoon, Kim, Jung Eun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663397/ https://www.ncbi.nlm.nih.gov/pubmed/33126764 http://dx.doi.org/10.3390/ijms21218050 |
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