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Heme-Induced Oxidation of Cysteine Groups of Myofilament Proteins Leads to Contractile Dysfunction of Permeabilized Human Skeletal Muscle Fibres

Heme released from red blood cells targets a number of cell components including the cytoskeleton. The purpose of the present study was to determine the impact of free heme (20–300 µM) on human skeletal muscle fibres made available during orthopedic surgery. Isometric force production and oxidative...

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Detalles Bibliográficos
Autores principales: Alvarado, Gerardo, Tóth, Attila, Csősz, Éva, Kalló, Gergő, Dankó, Katalin, Csernátony, Zoltán, Smith, Ann, Gram, Magnus, Akerström, Bo, Édes, István, Balla, György, Papp, Zoltán, Balla, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663642/
https://www.ncbi.nlm.nih.gov/pubmed/33142923
http://dx.doi.org/10.3390/ijms21218172

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