Newly Synthesized Fluorinated Cinnamylpiperazines Possessing Low In Vitro MAO-B Binding

Herein, we report on the synthesis and pharmacological evaluation of ten novel fluorinated cinnamylpiperazines as potential monoamine oxidase B (MAO-B) ligands. The designed derivatives consist of either cinnamyl or 2-fluorocinnamyl moieties connected to 2-fluoropyridylpiperazines. The three-step sy...

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Detalles Bibliográficos
Autores principales: I. Jevtić, Ivana, Lai, Thu Hang, Z. Penjišević, Jelena, Dukić-Stefanović, Sladjana, B. Andrić, Deana, Brust, Peter, Kostić-Rajačić, Sladjana V., Teodoro, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663645/
https://www.ncbi.nlm.nih.gov/pubmed/33114548
http://dx.doi.org/10.3390/molecules25214941

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