Cargando…

Mitocans Revisited: Mitochondrial Targeting as Efficient Anti-Cancer Therapy

Mitochondria are essential cellular organelles, controlling multiple signalling pathways critical for cell survival and cell death. Increasing evidence suggests that mitochondrial metabolism and functions are indispensable in tumorigenesis and cancer progression, rendering mitochondria and mitochond...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Lanfeng, Gopalan, Vinod, Holland, Olivia, Neuzil, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663685/ https://www.ncbi.nlm.nih.gov/pubmed/33114695 http://dx.doi.org/10.3390/ijms21217941

Ejemplares similares

Mitocanic Di- and Triterpenoid Rhodamine B Conjugates
por: Hoenke, Sophie, et al.
Publicado: (2020)

Redox-Cycling “Mitocans” as Effective New Developments in Anticancer Therapy
por: Bakalova, Rumiana, et al.
Publicado: (2023)

Targeting mitochondria as an anticancer strategy
por: Dong, Lanfeng, et al.
Publicado: (2019)

ONC212 is a Novel Mitocan Acting Synergistically with Glycolysis Inhibition in Pancreatic Cancer
por: Ferrarini, Isacco, et al.
Publicado: (2021)

Tolerable treatment of glioblastoma with redox-cycling ‘mitocans': a comparative study in vivo
por: Sumiyoshi, Akira, et al.
Publicado: (2023)

Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner
por: Yan, Bing, et al.
Publicado: (2015)

Effect of α-tocopheryloxy acetic acid, a vitamin E derivative mitocan, on the experimental infection of mice with Plasmodium yoelii
por: Kawamura, Kasumi, et al.
Publicado: (2021)

Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
por: Hubackova, Sona, et al.
Publicado: (2018)

Mitochondrial complex II and reactive oxygen species in disease and therapy
por: Hadrava Vanova, Katerina, et al.
Publicado: (2020)

Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy
por: Stemberkova‐Hubackova, Sona, et al.
Publicado: (2022)

Mechanisms of resistance to mitochondria-targeted therapy in pancreatic cancer
por: Boukalova, Stepana, et al.
Publicado: (2021)

Mitochondrial Function, Fatty Acid Metabolism, and Body Composition in the Hyperbilirubinemic Gunn Rat
por: Vidimce, Josif, et al.
Publicado: (2021)

Mitochondrial Syndromes Revisited
por: Orsucci, Daniele, et al.
Publicado: (2021)

Exosome-derived microRNAs in cancer metabolism: possible implications in cancer diagnostics and therapy
por: Tomasetti, Marco, et al.
Publicado: (2017)

Miro proteins and their role in mitochondrial transfer in cancer and beyond
por: Nahacka, Zuzana, et al.
Publicado: (2022)

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited
por: Plate, Karl H., et al.
Publicado: (2012)

Mitochondria on the move: Horizontal mitochondrial transfer in disease and health
por: Dong, Lan-Feng, et al.
Publicado: (2023)

Liposomal Delivery of miR-34b-5p Induced Cancer Cell Death in Thyroid Carcinoma
por: Maroof, Hamidreza, et al.
Publicado: (2018)

MitoTam-01 Trial: Mitochondrial Targeting as Plausible Approach to Cancer Therapy. Comment on Yap et al. Complex I Inhibitor of Oxidative Phosphorylation in Advanced Solid Tumors and Acute Myeloid Leukemia: Phase I Trials. Nat. Med. 2023, 29, 115–126
por: Neuzil, Jiri, et al.
Publicado: (2023)

Host-targeted therapy for tuberculosis: Time to revisit the concept
por: Desikan, Prabha, et al.
Publicado: (2018)

Revisiting the Anti-Cancer Toxicity of Clinically Approved Platinating Derivatives
por: Forgie, Benjamin N., et al.
Publicado: (2022)

Targeting Cancer Metabolism - Revisiting the Warburg Effects
por: Tran, Quangdon, et al.
Publicado: (2016)

Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2023)

Revisiting anti-angiogenic therapy for recurrent glioblastoma
por: Peters, Katherine B.
Publicado: (2019)

Mitochondrial permeability transition pore as a selective target for anti-cancer therapy
por: Suh, Dong H., et al.
Publicado: (2013)

Revisiting the Radiobiology of Targeted Alpha Therapy
por: Pouget, Jean-Pierre, et al.
Publicado: (2021)

The VEGF/VEGFR Axis Revisited: Implications for Cancer Therapy
por: Mabeta, Peace, et al.
Publicado: (2022)

Targeted Anti-Mitochondrial Therapy: The Future of Oncology
por: Taghizadeh-Hesary, Farzad, et al.
Publicado: (2022)

Revisiting the Role of Neurotrophic Factors in Inflammation
por: Morel, Lucas, et al.
Publicado: (2020)

Revisiting targeted therapy and immunotherapy for advanced cholangiocarcinoma
por: Du, Jiajia, et al.
Publicado: (2023)

Human Gene Control by Vital Oncogenes: Revisiting a Theoretical Model and Its Implications for Targeted Cancer Therapy
por: Willis, Rudolph E.
Publicado: (2011)

Oxidative stress and Rho GTPases in the biogenesis of tunnelling nanotubes: implications in disease and therapy
por: Raghavan, Abinaya, et al.
Publicado: (2021)

Targeting mTOR for Anti-Aging and Anti-Cancer Therapy
por: Fu, Wencheng, et al.
Publicado: (2023)

Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy
por: Baldari, Silvia, et al.
Publicado: (2022)

Na(+)/K(+)-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation
por: Bejček, Jiří, et al.
Publicado: (2021)

Revisiting the IGF-1R as a breast cancer target
por: Ekyalongo, Roudy Chiminch, et al.
Publicado: (2017)

Death receptors as targets for anti-cancer therapy
por: Papenfuss, Kerstin, et al.
Publicado: (2008)

Mitochondrial ATP-Dependent Proteases—Biological Function and Potential Anti-Cancer Targets
por: Feng, Yue, et al.
Publicado: (2021)

Mitochondrial Peroxiredoxin III is a Potential Target for Cancer Therapy
por: Song, In-Sung, et al.
Publicado: (2011)

Mitochondrial SLC25 Carriers: Novel Targets for Cancer Therapy
por: Rochette, Luc, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_juame5peh90jh046v376m2m4lb