Cargando…

Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study

The prevalence and mortality rates of diabetes are increasing globally, posing severe challenges to health systems. Acupuncture is used worldwide as a non-drug treatment for diabetes. However, empirical evidence of the effect of combined acupuncture and drug treatments on diabetic-associated mortali...

Descripción completa

Detalles Bibliográficos
Autores principales: Sui, Mengyun, Xue, Long, Ying, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663761/
https://www.ncbi.nlm.nih.gov/pubmed/33113774
http://dx.doi.org/10.3390/ijerph17217801
_version_ 1783609702509182976
author Sui, Mengyun
Xue, Long
Ying, Xiaohua
author_facet Sui, Mengyun
Xue, Long
Ying, Xiaohua
author_sort Sui, Mengyun
collection PubMed
description The prevalence and mortality rates of diabetes are increasing globally, posing severe challenges to health systems. Acupuncture is used worldwide as a non-drug treatment for diabetes. However, empirical evidence of the effect of combined acupuncture and drug treatments on diabetic-associated mortality is limited. This study aimed to examine this association of acupuncture treatment with mortality of type 2 diabetes based on real-world data. A four-year cohort study was conducted in Shanghai between 2015 and 2018, The database consisted of 37,718 patients (acupuncture group: 6865 type 2 diabetes mellitus (T2DM) patients, non-acupuncture (control) group: 30,853 T2DM patients) in 2016. The objective was to analyze the impact of receiving acupuncture prescriptions for diabetes in 2016 on all-cause mortality in 2018 based on real-world data. An Inverse Probability Weighted Regression Adjustment (IPWRA) and Propensity Score Matching (PSM) were used to minimize the bias due to potential confounding variables to increase the reliability of differences in comparisons between the two groups. Our inverse probability weighted regression results suggest that the coefficient of the key dependent variable of accepted acupuncture in 2016 was negative (coefficient: −0.0002; 95% CI: −0.0024–0.0019, p = 0.857), but it is not statistically significant. In robustness check, PSM with the nearest-neighbor method with replacement at a 1:4 ratio and 1:3 ratio and kernel matching showed that the average treatment effect was negative. Therefore, there was a negative correlation between acupuncture combined with other drugs and the mortality of diabetic patients, but it was not statistically significant.
format Online
Article
Text
id pubmed-7663761
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-76637612020-11-14 Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study Sui, Mengyun Xue, Long Ying, Xiaohua Int J Environ Res Public Health Article The prevalence and mortality rates of diabetes are increasing globally, posing severe challenges to health systems. Acupuncture is used worldwide as a non-drug treatment for diabetes. However, empirical evidence of the effect of combined acupuncture and drug treatments on diabetic-associated mortality is limited. This study aimed to examine this association of acupuncture treatment with mortality of type 2 diabetes based on real-world data. A four-year cohort study was conducted in Shanghai between 2015 and 2018, The database consisted of 37,718 patients (acupuncture group: 6865 type 2 diabetes mellitus (T2DM) patients, non-acupuncture (control) group: 30,853 T2DM patients) in 2016. The objective was to analyze the impact of receiving acupuncture prescriptions for diabetes in 2016 on all-cause mortality in 2018 based on real-world data. An Inverse Probability Weighted Regression Adjustment (IPWRA) and Propensity Score Matching (PSM) were used to minimize the bias due to potential confounding variables to increase the reliability of differences in comparisons between the two groups. Our inverse probability weighted regression results suggest that the coefficient of the key dependent variable of accepted acupuncture in 2016 was negative (coefficient: −0.0002; 95% CI: −0.0024–0.0019, p = 0.857), but it is not statistically significant. In robustness check, PSM with the nearest-neighbor method with replacement at a 1:4 ratio and 1:3 ratio and kernel matching showed that the average treatment effect was negative. Therefore, there was a negative correlation between acupuncture combined with other drugs and the mortality of diabetic patients, but it was not statistically significant. MDPI 2020-10-25 2020-11 /pmc/articles/PMC7663761/ /pubmed/33113774 http://dx.doi.org/10.3390/ijerph17217801 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sui, Mengyun
Xue, Long
Ying, Xiaohua
Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title_full Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title_fullStr Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title_full_unstemmed Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title_short Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study
title_sort association of acupuncture treatment with mortality of type 2 diabetes in china: evidence of a real-world study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663761/
https://www.ncbi.nlm.nih.gov/pubmed/33113774
http://dx.doi.org/10.3390/ijerph17217801
work_keys_str_mv AT suimengyun associationofacupuncturetreatmentwithmortalityoftype2diabetesinchinaevidenceofarealworldstudy
AT xuelong associationofacupuncturetreatmentwithmortalityoftype2diabetesinchinaevidenceofarealworldstudy
AT yingxiaohua associationofacupuncturetreatmentwithmortalityoftype2diabetesinchinaevidenceofarealworldstudy