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Chemical Space Exploration of Oxetanes

This paper focuses on new derivatives bearing an oxetane group to extend accessible chemical space for further identification of kinase inhibitors. The ability to modulate kinase activity represents an important therapeutic strategy for the treatment of human illnesses. Known as a nonclassical isost...

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Detalles Bibliográficos
Autores principales: Alves, Fernando Rodrigues de Sá, Couñago, Rafael M., Laufer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663787/
https://www.ncbi.nlm.nih.gov/pubmed/33147789
http://dx.doi.org/10.3390/ijms21218199