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Chemical Space Exploration of Oxetanes
This paper focuses on new derivatives bearing an oxetane group to extend accessible chemical space for further identification of kinase inhibitors. The ability to modulate kinase activity represents an important therapeutic strategy for the treatment of human illnesses. Known as a nonclassical isost...
Autores principales: | Alves, Fernando Rodrigues de Sá, Couñago, Rafael M., Laufer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663787/ https://www.ncbi.nlm.nih.gov/pubmed/33147789 http://dx.doi.org/10.3390/ijms21218199 |
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