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SCELLECTOR: ranking amplification bias in single cells using shallow sequencing

BACKGROUND: The study of mosaic mutation is important since it has been linked to cancer and various disorders. Single cell sequencing has become a powerful tool to study the genome of individual cells for the detection of mosaic mutations. The amount of DNA in a single cell needs to be amplified be...

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Detalles Bibliográficos
Autores principales:	Sarangi, Vivekananda, Jourdon, Alexandre, Bae, Taejeong, Panda, Arijit, Vaccarino, Flora, Abyzov, Alexej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663899/ https://www.ncbi.nlm.nih.gov/pubmed/33183232 http://dx.doi.org/10.1186/s12859-020-03858-y

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