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Relative Levels of Gli1 and Gli2 Determine the Response of Ventral Neural Stem Cells to Demyelination

Enhancing repair of myelin is an important therapeutic goal in many neurological disorders characterized by demyelination. In the healthy adult brain, ventral neural stem cells (vNSCs) in the subventricular zone, marked by GLI1 expression, do not generate oligodendrocytes. However, in response to de...

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Detalles Bibliográficos
Autores principales:	Radecki, Daniel Z., Messling, Heather M., Haggerty-Skeans, James R., Bhamidipati, Sai Krishna, Clawson, Elizabeth D., Overman, Christian A., Thatcher, Madison M., Salzer, James L., Samanta, Jayshree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664046/ https://www.ncbi.nlm.nih.gov/pubmed/33125874 http://dx.doi.org/10.1016/j.stemcr.2020.10.003

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