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Bipotent Progenitors Do Not Require Androgen Receptor for Luminal Specification during Prostate Organogenesis
Androgen receptor (AR) plays a fundamental role in most aspects of adult prostate homeostasis, and anti-androgen therapy represents the cornerstone of prostate cancer treatment. However, early prostate organogenesis takes place during pre-pubertal stages when androgen levels are low, raising the pos...
Autores principales: | Shibata, Maho, Epsi, Nusrat J., Xuan, Shouhong, Mitrofanova, Antonina, Shen, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664048/ https://www.ncbi.nlm.nih.gov/pubmed/33176121 http://dx.doi.org/10.1016/j.stemcr.2020.10.004 |
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