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Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells
The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a global unbiased proteomics approach we report that embryonic fibroblasts (MEFs) ca...
Autores principales: | Gupta, Manoj K., Vethe, Heidrun, Softic, Samir, Rao, Tata Nageswara, Wagh, Vilas, Shirakawa, Jun, Barsnes, Harald, Vaudel, Marc, Takatani, Tomozumi, Kahraman, Sevim, Sakaguchi, Masaji, Martinez, Rachael, Hu, Jiang, Bjørlykke, Yngvild, Raeder, Helge, Kulkarni, Rohit N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664055/ https://www.ncbi.nlm.nih.gov/pubmed/33125875 http://dx.doi.org/10.1016/j.stemcr.2020.10.001 |
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