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Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells

The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a global unbiased proteomics approach we report that embryonic fibroblasts (MEFs) ca...

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Detalles Bibliográficos
Autores principales: Gupta, Manoj K., Vethe, Heidrun, Softic, Samir, Rao, Tata Nageswara, Wagh, Vilas, Shirakawa, Jun, Barsnes, Harald, Vaudel, Marc, Takatani, Tomozumi, Kahraman, Sevim, Sakaguchi, Masaji, Martinez, Rachael, Hu, Jiang, Bjørlykke, Yngvild, Raeder, Helge, Kulkarni, Rohit N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664055/
https://www.ncbi.nlm.nih.gov/pubmed/33125875
http://dx.doi.org/10.1016/j.stemcr.2020.10.001

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