Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline with accumulation of amyloid beta (Aβ) and neurofibrillary tangles that usually begins 15–30 years before clinical diagnosis. Rodent models that recapitulate aggressive Aβ and/or the patholog...

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Detalles Bibliográficos
Autores principales: Saifullah, Md. Ali Bin, Komine, Okiru, Dong, Yutao, Fukumoto, Kazuya, Sobue, Akira, Endo, Fumito, Saito, Takashi, Saido, Takaomi C., Yamanaka, Koji, Mizoguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664057/
https://www.ncbi.nlm.nih.gov/pubmed/33183323
http://dx.doi.org/10.1186/s13041-020-00690-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664057/
https://www.ncbi.nlm.nih.gov/pubmed/33183323
http://dx.doi.org/10.1186/s13041-020-00690-6

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